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Clinical Evidence

Retatrutide clinical trials

Summaries of publicly reported investigational studies of retatrutide (LY3437943). Educational reference only — retatrutide remains investigational and is not approved for human use in most jurisdictions.

Phase 3 Ongoing 2024–present

Large-scale Phase 3 investigational programme

Expanded investigational programmes are assessing outcomes across larger cohorts. Retatrutide remains investigational and is not approved for human use in most jurisdictions.

Multiple large cohorts Read summary
Phase 2 Published 2022–2023

Dose-ranging study of retatrutide in adults with obesity

Mid-stage investigational trials explored a range of retatrutide doses and metabolic endpoints in adults with obesity, with results reported in the peer-reviewed literature.

338 adults Read summary
Phase 1 Published 2019–2021

First-in-human safety and pharmacokinetics of retatrutide

Initial investigational studies characterised the pharmacokinetics and tolerability of retatrutide (LY3437943), establishing the groundwork for later dose-ranging research.

Healthy adult volunteers Read summary

These summaries describe publicly reported research for educational purposes. They are not therapeutic claims and do not constitute medical advice. Products supplied by OnlineRetatrutide are strictly for in-vitro laboratory research.