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Phase 3 Ongoing

Large-scale Phase 3 investigational programme

2024–present Multiple large cohorts

Expanded investigational programmes are assessing outcomes across larger cohorts. Retatrutide remains investigational and is not approved for human use in most jurisdictions.

Study overview

This summary describes publicly reported investigational research on retatrutide (LY3437943). Full study design, endpoints and outcome data can be added here through the classic editor.

Relevance for researchers

Published trial data provides context for laboratory reference material and helps researchers relate in-vitro findings to the wider investigational programme. See our References page for the underlying literature.

Educational summary only — not a therapeutic claim and not medical advice.

Educational summary of publicly reported research. Not a therapeutic claim and not medical advice. Retatrutide is investigational and not approved for human use in most jurisdictions.

More clinical trials

Phase 2 2022–2023

Dose-ranging study of retatrutide in adults with obesity

Mid-stage investigational trials explored a range of retatrutide doses and metabolic endpoints in adults with obesity, with results…

Phase 1 2019–2021

First-in-human safety and pharmacokinetics of retatrutide

Initial investigational studies characterised the pharmacokinetics and tolerability of retatrutide (LY3437943), establishing the groundwork for later dose-ranging research.